Astellas (4503) Stock Price, Fundamentals & Analysis
Price
2,399 JPY
+1.7%
Last trade: Sep 25, 2026, 03:30 PM GMT+9
Updated: Sep 27, 2026, 06:31 PM GMT+9
Price history
Over the past year 4503 traded between 1,575.5 JPY and 2,657.5 JPY, closing at 2,399 JPY on Sep 25, 2026.
Key statistics
| Market cap | 4.3T JPY |
|---|---|
| P/E ratio (TTM) | 14.8 |
| Forward P/E | 31.7 |
| EPS (TTM) | 162.17 JPY |
| Dividend yield | 3.33% |
| Annual dividend | 80 JPY |
| Ex-dividend date | Sep 29, 2026 |
| Payout ratio | 48% |
| 52-week range | 1,557.5 – 2,717 |
| 52-week change | 49.9% |
| Beta | 0.09 |
| Price / book | 2.21 |
| Revenue (TTM) | 2.27T JPY |
| Revenue growth (YoY) | 26.7% |
| Gross margin | 80.8% |
| Operating margin | 28.9% |
| Profit margin | 16% |
| Return on equity | 21.3% |
| Debt / equity | 30.3 |
| Volume | 5,627,600 |
| Average volume | 6,387,138 |
| Next earnings | Oct 29, 2026 |
| Exchange | Tokyo |
Profile
- Sector
- Healthcare
- Industry
- Drug Manufacturers - General
- Employees
- 14,099
- Headquarters
- Chuo, Japan
- Website
- astellas.com
Astellas Pharma Inc. engages in the research, development, manufacture, sale, and supply of pharmaceuticals in Japan and internationally. The company offers XTANDI, a treatment for prostate cancer; XOSPATA, a treatment for acute myeloid leukemia; VYLOY, a treatment for gastric adenocarcinoma and esophagogastric junction adenocarcinoma; and PADCEV, a treatment for patients with metastatic urothelial carcinoma. It also provides VEOZAH, a treatment for vasomotor symptoms associated with menopause; IZERVAY, a treatment for age-related macular degeneration with geographic atrophy; Betanis/Myrabetriq/BETMIGA, a treatment for overactive bladder; and Prograf, an immunosuppressant. It offers its products to oncology, ophthalmology, urology, immunology, and women's health areas. The company was formerly known as Yamanouchi Pharmaceutical Co. Ltd. and changed its name to Astellas Pharma Inc. in April 2005. Astellas Pharma Inc. was founded in 1923 and is headquartered in Chuo, Japan.
Overview
What 4503 does
Astellas (4503) is a stock in the Healthcare sector, specifically in the Drug Manufacturers - General industry, listed on the Tokyo Stock Exchange. The company researches, develops, manufactures, sells, and supplies pharmaceuticals in Japan and internationally. Its portfolio includes treatments for prostate cancer, acute myeloid leukemia, gastric adenocarcinoma, and metastatic urothelial carcinoma, as well as therapies for menopause symptoms, age-related macular degeneration, overactive bladder, and immunosuppression. Astellas is part of the Japanese equity market and is often compared with peers such as Takeda Pharmaceutical (4502), Chugai Pharmaceutical (4519), and Eisai (4523).
Key numbers explained
- Price: 2,399 JPY is the latest trading price of one share.
- Trailing P/E ratio: 14.8 shows the price relative to the last 12 months of earnings; a lower number can suggest the stock is cheaper relative to earnings, but context matters.
- Forward P/E ratio: 31.7 uses expected future earnings, reflecting what investors are paying for growth expectations.
- Dividend yield: 3.33% is the annual dividend as a percentage of the current price, indicating the cash return shareholders receive.
- Ex-dividend date: Sep 29, 2026 is the date by which you must own the stock to receive the next dividend payment.
- Beta: 0.09 suggests the stock’s price tends to move much less than the overall market.
- 52-week range: 1,557.5 – 2,717 shows the lowest and highest prices over the past year.
- Revenue growth: 26.7% year over year indicates how quickly the company’s top line has expanded.
What to watch
Investors tracking Astellas (4503) often watch its upcoming earnings release on Oct 29, 2026, which can move the stock. The 48% share of earnings paid out as dividends highlights the company’s payout policy, while the 30.3% debt-to-equity ratio reflects its use of borrowed capital. Being part of the Nikkei 225 index means it is a large, liquid stock often followed by institutional investors. Broader factors that typically affect this kind of stock include drug approval cycles, patent expirations, currency movements, and healthcare policy changes.
Latest news & filings
No recent headlines.
Frequently asked questions
Does 4503 pay a dividend?
Yes. Astellas pays a dividend with a yield of 3.33%, and the next ex-dividend date is Sep 29, 2026.
What is the 4503 P/E ratio?
The trailing P/E ratio is 14.8, while the forward P/E ratio based on expected earnings is 31.7.
Where can I buy 4503?
You can buy Astellas (4503) on the Tokyo Stock Exchange through a broker that offers access to Japanese equities.
What does Astellas do?
Astellas researches, develops, manufactures, and sells pharmaceuticals, including treatments for cancer, overactive bladder, and age-related macular degeneration.
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