Vertex Pharmaceuticals

Vertex Pharmaceuticals (VRTX) Stock Price, Fundamentals & Analysis

StockUSS&P 500Health Care

Price

516.34 USD

+0.26%

Price history

Over the past year VRTX traded between 376.62 USD and 557.96 USD, closing at 516.34 USD on Sep 24, 2026.

Key statistics

Market cap130.79B USD
P/E ratio (TTM)30.1
Forward P/E25.7
EPS (TTM)17.16 USD
Dividend yield0%
Annual dividend0 USD
Payout ratio0%
52-week range374.17 – 560.25
52-week change36.7%
Beta0.32
Price / book6.46
Revenue (TTM)12.59B USD
Revenue growth (YoY)12.5%
Gross margin55%
Operating margin38.1%
Profit margin35%
Return on equity23.5%
Debt / equity9.8
Volume1,213,419
Average volume1,410,930
Next earningsNov 2, 2026
ExchangeNasdaqGS

Profile

Sector
Healthcare
Industry
Biotechnology
Employees
6,400
Headquarters
Boston, United States
Website
vrtx.com

Vertex Pharmaceuticals Incorporated operates as a biotechnology company in the United States, Europe, and internationally. The company offers transformative medicines for people with serious diseases with a focus on specialty markets, such as cystic fibrosis (CF), sickle cell disease (SCD), transfusion dependent beta thalassemia (TDT), and acute pain. It markets TRIKAFTA/KAFTRIO for people with CF with at least one F508del mutation for 2 years of age and older; ALYFTREK for the treatment for people with CF 6 years of age and older; SYMDEKO/SYMKEVI for treatment of patients with CF 6 years of age and older; ORKAMBI for CF patients 1 year or older; and KALYDECO for the treatment of patients with 1 month or older who have CF with ivacaftor.

Overview

What VRTX does

Vertex Pharmaceuticals (VRTX) is a biotechnology company headquartered in Boston, United States, operating in the Healthcare sector. It develops transformative medicines for serious diseases, with a focus on cystic fibrosis (CF), sickle cell disease (TDT), transfusion-dependent beta thalassemia, and acute pain. Key products include TRIKAFTA/KAFTRIO for CF patients with at least one F508del mutation aged 2 years and older, ALYFTREK for CF patients 6 years and older, SYMDEKO/SYMKEVI for CF patients 6 years and older, ORKAMBI for CF patients 1 year or older, and KALYDECO for patients 1 month and older with CF who have an ivacaftor-responsive mutation.

Key numbers explained

  • $516.34 is the current share price, representing the cost to buy one share on the US market.
  • The trailing P/E ratio of 30.1 shows how much investors pay per dollar of the company's last 12 months' earnings; a higher number can reflect growth expectations.
  • The forward P/E ratio of 25.7 uses expected future earnings, offering a look at how the market values what the company might earn next.
  • Earnings per share (trailing 12 months) of $17.16 is the portion of the company's profit allocated to each outstanding share.
  • Dividend yield of 0% and 0% of earnings paid out as dividends mean the company currently does not distribute cash to shareholders.
  • Beta of 0.32 suggests the stock tends to be less volatile than the overall market, often moving about a third as much as the broad market.
  • Market capitalisation of 130.79B USD is the total value of all outstanding shares, placing Vertex among large-cap companies.
  • Price change over the last 52 weeks of 36.7% indicates the stock's total return from one year ago to today, including price movement.

Recent news

  • Vertex posted positive Phase II data on a kidney disease drug.
  • TD Cowen adjusted its price target on Vertex Pharmaceuticals to $550 from $525, maintaining a Buy rating.
  • Jefferies adjusted its price target on Vertex Pharmaceuticals to $640 from $633, maintaining a Buy rating.

What to watch

As a Healthcare biotechnology stock, Vertex Pharmaceuticals can be sensitive to clinical trial results, regulatory decisions on new treatments, and broader sector trends. Investors often compare it with peers such as Illumina, Inc. (ILMN), Intuitive Surgical (ISRG), and Thermo Fisher Scientific (TMO) to contextualise its growth and valuation. The company is part of the S&P 500, which means it is a large, widely followed component of the US equity market.

Latest news & filings

Frequently asked questions

Does VRTX pay a dividend?

No. Vertex Pharmaceuticals currently has a dividend yield of 0% and pays out 0% of its earnings as dividends.

What is the VRTX P/E ratio?

The trailing P/E ratio is 30.1, and the forward P/E ratio based on expected earnings is 25.7.

Where can I buy VRTX?

VRTX trades on the US market as a stock, so it can be purchased through any brokerage that offers access to US-listed equities.

What does Vertex Pharmaceuticals do?

It is a biotechnology company focused on developing transformative medicines for serious diseases, particularly cystic fibrosis, sickle cell disease, and acute pain.

How big is Vertex Pharmaceuticals?

It has a market capitalisation of 130.79 billion USD and approximately 6,400 employees.

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Data as of Sep 23, 2026. Sources: Yahoo Finance, Bucharest Stock Exchange.

For information and education only — not investment advice. Prices may be delayed. The overview is generated with AI from the data shown on this page.